AB1469 SPANISH TRANSLATION AND CROSS-CULTURAL ADAPTATION OF THE mSQUASH

Background Regular physical activity is recommended for all patients in the ASAS/EULAR recommendations management of axial spondyloarthritis (axSpA). However, there a lack outcome measures that assess amount and type with axSpA. For this matter, modified Short QUestionnaire to Assess Health enhancing (mSQUASH) was developed validated, originally Dutch1. Objectives To translate cross-culturally adapt mSQUASH into Spanish test equivalence translated version Methods The then back-translated Dutch, following forward-backward procedure as described by Beaton 2 (Figure 1). Two bi-lingual translators (native speakers European Spanish) produced independent forward translations item content, response options, instructions Spanish. Both versions were harmonized meeting among translators, methodologist rheumatologist consensual version. Another translator speaker Dutch), blinded original version, back synthesized Dutch. An expert committee, including one rheumatologist, reached consensus on discrepancies, ensuring between Dutch versions, pre-final mSQUASH. field cognitive debriefing involved sample 10 axSpA covering full spectrum disease -radiographic (r-axSpA) non-radiographic (nr-axSpA)- different gender, age, duration, educational background. Each patient interviewed check understandability, interpretation cultural relevance translation. Figure 1. Cross-cultural adaptation Results translation process completed without major complications procedure. first needed several iterations due small discrepancies wording. Back-translation performed difficulties, committee agreed upon final questionnaire. A total participated (Table Seven male, mean age (SD) 38.9 (14.4) years; 6 had r-axSpA, 9 HLA-B27+. Cognitive showed questionnaire be, relevant, understandable comprehensive. preliminary accepted minor modifications. As result interviews, spelling errors corrected, wording categories homogenized (“despacio/ligero”). Besides, term “colegio”- literally from “school”- found not comprehensive enough reflect possibilities education (i.e. it does include university), so adapted “el lugar de estudio”. Table Patients’ characteristics # Gender Age Working status Education subtype Disease duration HLA-B27 Drug BASDAI 1 Male 63 University r-axSpA 35 y + NSAIDs 2.3 24 Student Secondary 0 3 37 5 ADA 2.5 4 66 Retired 23 IFN 3.1 29 11 Female 26 nr-axSpA - 7 ETA 4.5 8 12 GOL 40 45 Unemployed Primary 8.2 Conclusion resulting good linguistic face validity according test, revealing potential use both clinical practice research settings. In order conclude cross-cultural Spanish, next step assessment psychometric properties References [1]Beaton DE, et al. Spine. 2000; 25:3186-91 [2]Carbo Semin Arthritis Rheum. 2021; 51:719-27 Disclosure Interests Diego Benavent Speakers bureau: Jannsen, Roche, Grant/research support from: Novartis, Andrea Jochems: None declared, DORA PASCUAL-SALCEDO Pfizer, Menarini, Takeda, Abvvie., Gijs Chamaida Plasencia Abbvie, Lilly, Sandoz, Sanofi, Biogen, Roche Pfizer Sofia Ramiro Eli MSD, UCB, Consultant of: AbbVie, Galapagos, Suzanne Arends: Anneke Spoorenberg Pfizer; Alejandro Balsa BMS, Nordic Pharma, Gebro, Victoria Navarro-Compán Janssen, UCB AbbVie Novartis